Tuberculosis serological data from the Netherlands 1966-1973 (aggregated)

A study of tuberculosis conducted in the Netherlands. Schoolchildren, aged between 6 and 18 years, were tested using the tuberculin skin test.

Usage

tb_nl_1966_1973

Format

A data frame with 5 variables:

age

Age group

pos

Number of seropositive individuals

tot

Total number of individuals surveyed

gender

Gender of cohort (unsure what 0 and 1 means)

birthyr

Birth year of cohort

Source

Nagelkerke, N., Heisterkamp, S., Borgdorff, M., Broekmans, J. and Van Houwelingen, H. (1999), Semi-parametric estimation of age-time specific infection incidence from serial prevalence data. Statist. Med., 18: 307-320. doi:10.1002/(SICI)1097-0258(19990215)18:3<307::AID-SIM15>3.0.CO;2-Z

Examples

# Reproduce Fig 4.6, p.70
age <- tb_nl_1966_1973$age
birthyr <- tb_nl_1966_1973$birthyr
pos <- tb_nl_1966_1973$pos
tot <- tb_nl_1966_1973$tot
# left panel
plot(age, pos / tot,
  pch = 16, cex = 0.00005 * tot, xlab = "age",
  ylab = "prevalence", xlim = c(6, 18)
)

# right panel
plot(birthyr, pos / tot,
  pch = 16, cex = 0.00005 * tot, xlab = "year", ylab = "prevalence"
)