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Dataset

Hepatitis A

hav_be_1993_1994
Hepatitis A serological data from Belgium in 1993 and 1994 (aggregated)
hav_be_2002
Hepatitis A serological data from Belgium in 2002 (line listing)
hav_bg_1964
Hepatitis A serological data from Bulgaria in 1964 (aggregated)

Hepatitis B

hbv_ru_1999
Hepatitis B serological data from Russia in 1999 (aggregated)

Hepatitis C

hcv_be_2006
Hepatitis C serological data from Belgium in 2006 (line listing)

Mumps

mumps_uk_1986_1987
Mumps serological data from the UK in 1986 and 1987 (aggregated)

Parvo B19

parvob19_be_2001_2003
Parvo B19 serological data from Belgium from 2001-2003 (line listing)
parvob19_ew_1996
Parvo B19 serological data from England and Wales in 1996 (line listing)
parvob19_fi_1997_1998
Parvo B19 serological data from Finland from 1997-1998 (line listing)
parvob19_it_2003_2004
Parvo B19 serological data from Italy from 2003-2004 (line listing)
parvob19_pl_1995_2004
Parvo B19 serological data from Poland from 1995-2004 (line listing)

Rubella

rubella_uk_1986_1987
Rubella serological data from the UK in 1986 and 1987 (aggregated)

Tuberculosis

tb_nl_1966_1973
Tuberculosis serological data from the Netherlands 1966-1973 (aggregated)

VZV

vzv_be_1999_2000
VZV serological data from Belgium (Flanders) from 1999-2000 (aggregated)
vzv_be_2001_2003
VZV serological data from Belgium from 2001-2003 (line listing)

Multivariate data

rubella_mumps_uk
Rubella - Mumps data from the UK (aggregated)
vzv_parvo_be
VZV and Parvovirus B19 serological data in Belgium (line listing)

Models

polynomial_model()
Polynomial models
farrington_model()
The Farrington (1990) model.
weibull_model()
The Weibull model.
fp_model()
A fractional polynomial model.
lp_model()
A local polynomial model.
hierarchical_bayesian_model()
Hierarchical Bayesian Model
penalized_spline_model()
Penalized Spline model
mixture_model()
Fit a mixture model to classify serostatus
estimate_from_mixture()
Estimate seroprevalence and FOI from a fixed mixture model
age_time_model()
Age-time varying seroprevalence

Plotting functions

plot_corrected_prev()
Plot output for corrected_prevalence
plot_standard_curve()
Visualize standard curves for each plate
plot_titer_qc()
Quality control plot
plot_gcv()
Plotting GCV values with respect to different nn-s and h-s parameters.
plot(<polynomial_model>)
plot() overloading for polynomial model
plot(<farrington_model>)
plot() overloading for Farrington model
plot(<weibull_model>)
plot() overloading for Weibull model
plot(<fp_model>)
plot() overloading for fractional polynomial model
plot(<lp_model>)
plot() overloading for local polynomial model
plot(<hierarchical_bayesian_model>)
plot() overloading for hierarchical_bayesian_model
plot(<penalized_spline_model>)
plot() overloading for penalized spline
plot(<mixture_model>)
plot() overloading for mixture model
plot(<estimate_from_mixture>)
plot() overloading for result of estimate_from_mixture
plot(<age_time_model>)
Plot output for age_time_model
set_plot_style()
Helper to adjust styling of a plot
add_thresholds()
Visualize positive threshold at different dilution factors

Other utilities

serosv serosv-package
serosv: model infectious disease parameters
est_foi()
Estimate force of infection
pava()
Monotonize seroprevalence
to_titer()
Convert assay readings to titers
correct_prevalence()
Estimate the true sero prevalence using Frequentist/Bayesian estimation
transform_data()
Aggregate data
standardize_data()
Standardize raw serological test data for titer conversion
compare_models()
Generate table of metrics for model comparison
compute_ci(<default>)
Compute confidence interval for a model of serosv
compute_ci(<fp_model>)
Compute confidence interval for fractional polynomial model
compute_ci(<lp_model>)
Compute confidence interval for local polynomial model
compute_ci(<weibull_model>)
Compute confidence interval for Weibull model
compute_ci(<penalized_spline_model>)
Compute confidence interval for penalized_spline_model
compute_ci(<mixture_model>)
Compute confidence interval for mixture model
compute_ci(<age_time_model>)
Compute confidence interval for time age model
compute_ci(<hierarchical_bayesian_model>)
Compute 95% credible interval for hierarchical Bayesian model
predict(<age_time_model>)
Predict from the age_time_mdoel
predict(<farrington_model>)
Prediction for serosv Farrington model
predict(<fp_model>)
Prediction for serosv fractional polynomial model
predict(<hierarchical_bayesian_model>)
Predict from an hierarchical bayesian model
predict(<lp_model>)
Prediction for serosv local polynomial model
predict(<penalized_spline_model>)
Prediction for serosv penalized spline model
predict(<weibull_model>)
Prediction for serosv Weibull model
predict(<polynomial_model>)
Prediction for serosv polynomial model
find_best_fp_powers()
Returns the powers of the fractional polynomial model which has the lowest deviance score.